Now updated: the definitive neuroscience resource—from Eric R. Kandel, MD (winner of the Nobel Prize in 2000); James H. Schwartz, MD, PhD; Thomas M. Jessell, PhD; Steven A. Siegelbaum, PhD; and A. J. Hudspeth, PhD 900 full-color illustrations Deciphering the link between the human brain and behavior has always been one of the most intriguing—and often challenging—aspects of scientific endeavor. The sequencing of the human genome, and advances in molecular biology, have illuminated the pathogenesis of many neurological diseases and have propelled our knowledge of how the brain controls behavior. To grasp the wider implications of these developments and gain a fundamental understanding of this dynamic, fast-moving field, Principles of Neuroscience stands alone as the most authoritative andatient; circulation of the brain; the blood-brain barrier, choroid plexus, and cerebrospinal fluid; neural networks; and theoretical approaches to neuroscience