This book aims to highlight all the existing information available on first and mid-trimester imaging of palate in prenatal ultrasound and to develop a methodical approach in imaging the palate. As formation of the palate is completed by 11 weeks of gestation and as there are no evolving changes in palatine anatomy at the mid-trimester, diagnosis of palatine clefts can now completely be shifted to late first-trimester. First-trimester evaluation of palate is now gaining importance and a number of techniques have currently been proposed by different authors. This book covers the existing literature and recent 2D and 3D techniques in evaluating palate and helps in the early detection of palatine clefts in the first trimester. Orofacial clefting is one of the most common birth defects and the burden of it in developing countries is substantial. This book helps in improving the counseling options for the obstetrician and the couple early in gestation.