The book covers all the radiation safety aspects while working with unsealed radionuclides. Radiation safety plays a significant role in routine nuclear medicine practices and is necessary to protect occupational workers, patients, members of the general public and the environment. A fair knowledge of radiation safety is expected from all nuclear medicine professionals. Chapters include basics of radiation physics, biological bases of radiation protection, planning and design of nuclear medicine facilities, cyclotron and high dose therapy facilities, radiation safety considerations in nuclear medicine, cyclotron while preparing radiopharmaceuticals.