Strong roots in basic science and research enhance clinical practice. This book is a rich source of information for basic scientists and translational researchers who focus on musculoskeletal tissues and for orthopedic and trauma surgeons seeking relevant up-to-date information on molecular biology and the mechanics of musculoskeletal tissue repair and regeneration.The book opens by discussing biomaterials and biomechanics, with detailed attention to the biologic response to implants and biomaterials and to the surface modification of implants, an important emerging research field. Finite element analysis, mechanical testing standards and gait analysis are covered. All these chapters are strongly connected to clinical applications.