Tumors involving peripheral nerves may be extremely challenging lesions to diagnose and treat.  In order to optimize their management,  physicians should have a thorough knowledge of peripheral nerve anatomy and pathology (both gross and microscopic), as well as familiarity with microsurgical techniques and intraoperative neurophysiological recording.This  compendium deals with all aspects of tumors affecting peripheral nerves,  from diagnosis to treatment; the topics it addresses range  from epidemiology, anatomy, physiology, pathology, and clinical diagnosis to electrophysiology, imaging, genetic/cytomolecular aspects. Surgical approaches, biopsies and resection of various benign, malignant and pseudo-tumoral lesions, plexus tumors (both brachial and lumbosacral), and adjunctive treatment modalities and pain-related issues are described in detail.