This book addresses the challenges clinicians face when working with patients facing complicated medical diagnosis for which transplantation is considered. Written by experts in transplant psychiatry, each chapter approaches a common psychiatric challenge faced by transplant candidates and recipients. Chapters meticulously share clinical expertise that provides a framework for future discussions without neglecting the fact that each transplant patient is unique in the complexity of their medical diagnosis. Additionally, the book examines complex issues including transplant-related posttraumatic stress disorder, post-transplant cognitive impairment, the collaboration between mental health and transplant clinicians, substance use and a wide range of other complicated topics.