This book on migraine is the first machine-generated scientific book in medicine published by Springer Nature, and reflects a new publication format which focuses on literature reviews: state-of-the-art computer algorithms were applied to select relevant sources from Springer Nature journal articles, rearrange them in a topical order, and provide short summaries of these articles. The result is the auto-summarization of current texts, organized by means of a similarity-based clustering routine in coherent chapters and sections. The human intervention of a world-renowned expert in this field grants the scientific soundness and appropriate organization of the contents identified. The AI-based approach seemed especially suitable to provide an innovative perspective as the topics are indeed both complex, interdisciplinary and multidisciplinary, as is migraine, the most important among the chronic non communicable diseases under the age of 50s.