This comprehensive, case-based resource provides the state-of-the-art knowledge that can help readers improve access and optimize delivery of stroke thrombectomy.  Improving access to stroke is of particular importance because patients often misinterpret their symptoms or cannot speak for themselves if they have aphasia.  More importantly, access needs to be organized because stroke therapies are all extremely time-sensitive.  Scalable, choreographed protocols are necessary for emergency medical systems to  capture  stroke patients and automatically transport and triage to time-sensitive treatments.  Many of the chapters in the first section on Fundamentals and Systems provide valuable insight in improving access to stroke care.