The Reference Manual for Humanitarian Health Professionals: Missioncraft in Disaster Relief is a hands-on resource written for disaster relief practitioners, educators, and researchers working in clinical medicine, public health, or disaster management.     Missioncraft  is the art and science of preparing and conducting successful field operations. This manual provides state-of-the-art technical reference information developed from inter-disciplinary, inter-agency, and international best practices. It also provides tools and templates for health professionals addressing key disaster issues including security stabilization, rapid epidemiological assessment, environmental health, disease surveillance, epidemic preparedness, communicable disease control, standardized case management, referral practices, laboratory diagnostics, and medical logistics.