The most complete, in-depth coverage of the field available today in one source! It focuses particularly on etiology and pathogenesis, disease mechanisms and includes all of the appropriate recent genetic, molecular and basic science data. More than 5,400 illustrations provide diagnostic assistance of clinical variants to support clinicopathological correlation and differential diagnoses. The 3rd Edition has been completely reorganized and redesigned to better meet the diagnostic challenges faced in everyday practice. Histologic and diagnostic pitfalls are highlighted throughout and include detailed references for all relevant conditions.