This book reviews the potential therapeutic and reproductive applications of mesenchymal stem cells in veterinary regenerative and reproductive medicine. The systemic approach focuses on musculoskeletal structures like cartilage, bone, muscle, tendon, ligaments and nervous tissues. It also focuses on other body systems like gastrointestinal, cardiovascular, urogenital, respiratory and integumentary system. Besides, the special glands or organs like endocrine glands and eye and its adnexa are also focused. The book chapters discusses the problems and the need for regenerative medicine employing MSCs. It provides an ex vivo basis of MSCs therapeutics and reproductive potential followed by their in vivo applications. The book further provides an understanding on the behavior and mechanisms of action of mesenchymal stem cells. The book also abridges challenges and provides future prospects of mesenchymal stem cells in clinical and reproductive applications.