Known for generations as the most comprehensive foundational text on medical microbiology, Schaechter s Mechanisms of Microbial Disease delivers a thorough understanding of microbial agents and the pathophysiology of microbial diseases. This trusted text is universally praised for  telling the story of a pathogen  in an engaging way, facilitating learning and recall by emphasizing unifying principles and paradigms. Content is uniquely organized by microbial class and by organ system, making it equally at home in traditional and systems-based curricula.       This updated 6th Edition reflects the latest advances in the field, including significant enhancements to the coverage of serious threats to global health (including COVID-19), respiratory and childhood viruses, and sexually transmitted diseases. New illustrations and additional learning features further clarify concepts, reinforce understanding, and help users confidently prepare for board exams and beyond.