This book offers clear, practical, and simple recommendations for treating patients with personality disorders. The goals of the book are twofold: 1) to describe the essential elements of Transference-Focused Psychotherapy (TFP), an evidence-based treatment for Borderline Personality Disorder, and 2) to describe how core principles and techniques of TFP can be used in a variety of settings to improve clinical management of patients with a broad spectrum of personality pathology, even when patients are not engaged in individual psychotherapy. A short introduction outlines in concise language the core elements of TFP and its origins in object relations theory. The book then takes the clinician through the process of: 1) comprehensive diagnosis, 2) negotiation of the treatment frame, and 3) the overarching strategies, techniques, and tactics used in the individual treatment, including helpful, accessible clinical vignettes.