This text provides background on the history of perinatal psychiatry, and discusses future directions in the field. It clearly defines perinatal mood and anxiety disorders (PMADs), which are the most common complication of pregnancy. When left untreated, PMADs are morbid and devastating for both the patient and their entire family. It reviews gold standard recommendations for the treatment of PMADs, including evidence-based psychotherapies, as well as risk-benefit analysis of psychotropic medication use in pregnancy and lactation. Additionally, common presentations of depression, anxiety, and trauma in pregnancy and postpartum women, as well as mania, psychosis, suicidal and homicidal thoughts are reviewed. Women s Mood Disorders: A Clinician s Guide to Perinatal Psychiatry highlights special considerations in pregnancy, including teenage pregnancies, hyperemesis gravidum, eating disorders, substance abuse disorders, as well as infertility, miscarriage and loss.