This issue examines recent developments in reconstruction in the head and neck region. Material is arranged anatomically: mandible, maxillary defect, laryngo-esophageal, skull defects, tongue, lip/perioral, etc. Throughout, novel techniques are compared with traditional techniques in terms of cost-effectiveness and outcomes. Future research, include the possibility of homotransplatation of facial parts, also is addressed. Of interest to anyone involved in surgery involving the head and neck, including plastic surgeons, oral and maxillofacial surgeons, and otolaryngologists.