The pharmacology, overdoses, and poisonings section from Irwin and Rippe´s Manual of Intensive Care Medicine, Fourth Edition, has now been expanded into a complete, stand-alone Spiral Manual. This new Manual of Overdoses and Poisonings is a practica l quick-reference bedside guide to the evaluation and treatment of toxic or potentially toxic drug and chemical exposures. The first chapter presents a general approach to differential diagnosis, diagnosis, and treatment of poisoning. Subsequent cha pters focus on specific drugs, chemicals, and toxidromes and provide details on clinical presentation, pathophysiology, diagnosis, and treatment. Chapters are formatted to allow quick access to essential information and include annotated references.