This book presents original case studies performed on dedicated PET-CT devices and showcases common and uncommon cancers and the latest PET-CT applications for neurological, pediatric, and cardiovascular disorders. This authoritative book, now in its Second Edition, presents correlative three-dimensional cross-sectional PET and CT images that highlight pathological findings. Each case example is accompanied by a concise explanation of the patient history and interpretation of the PET-CT study. Pearls and pitfalls and insightful discussions are included to assist in the understanding of pathology, diagnosis, and imaging approaches. The book also discusses pathophysiology and technical artifacts and summarizes the advantages and limitations of using this technology in the clinical setting.