This edited volume, featuring five new chapters from invited authors, provides an updated and evidence-based explanation of leadership within a healthcare environment. The book discusses new insights garnered from recent research into the importance of leadership in health system redesign and highlights the practice of shared or distributed health care leadership. New chapters covering LEADS in a national, regional, Indigenous, health profession, and people-centred care context provide new insights into how LEADS is being put to work to transform health systems. The LEADS framework has been refreshed in relation to each of its different elements and tools, with an emphasis on providing real-life examples of how LEADS has been put to work. LEADS is also explained as a change leadership model and in relation to how it helps to level the playing field in terms of gender and diversity in health leadership.