Endoscopic spinal surgery has become popular due its procedure-related benefits. The biportal endoscopic surgery is a recent technique, which has gained popularity in Asia, Europe, and Latin America since it can be applied to treat many diseases of the whole spine as cervical, thoracic, lumbar and sacral. Divided into thirty-four chapters, this first-ever book on unilateral biportal endoscopic spine surgery presents the technique history review and its current applications; the currently available technology and basic principles of this surgery: anesthesia, position, and operative room setup; endoscopic instruments, hydrostatic pressure, and intraoperative radiology; as well as anatomical considerations of basic approaches. It also details the techniques to resolve lumbar, cervical and thoracic spine diseases.