This book examines the role of technology-assisted interventions for substance use disorders (SUD). It considers this topic alongside the dramatic increase in SUDs and associated harm in the United States  past decade.Chapters relay the impact and effectiveness of technology-assisted interventions, which include telemedicine, assisted therapies, and support. These treatments not only offer practical care but also address the issue of access to care, particularly in the wake of the global pandemic (COVID-19). Organized into three sections, section one covers the use of telemedicine and technology-assisted therapies as it relates to the treatment of various SUDs, achieving recovery and maintenance. Each chapter will expand on a specific aspect of technology-assisted intervention. Following this, section two explores the differences in technology-assisted interventions and approaches while taking into account age, gender, sexuality, identity, and psychosocial factors.