This book systematically summarizes classic imaging signs characteristics and theory for whole body imaging, serving as a clinical guide for the understanding, prevention, and diagnosis of miscellaneous entities. In recent years, with the rapid evolution of modern imaging modalities, radiology has secured an irreplaceable role in diagnosis within standard clinical practice and being familiar with radiological signs has become essential.The book provides a multimodality review of more than 300 commonly utilized radiologic signs in radiography, CT, MRI, US, angiography, and nuclear medicine, including PET-CT. It is designed to enhance recognition of specific imaging patterns and enable the image interpreter to confidently reach an accurate diagnosis.