Interventional Neuroradiology is a relatively new field that uses state of the art equipment to treat complex cerebrovascular problems from within the blood vessels. Minimally invasive endovascular treatments have had a major impact on the treatment of complex cerebrovascular disorders. This issue focuses on some of the conditions that are currently being treated include cerebral aneurysms, arterio-venous malformations, tumors of the brain, spinal cord and head and neck. Exciting new therapies for stroke prevention, pioneered by leading neurosurgeons, are also included.