This book introduces readers to the basics of Advanced Practice Nursing (APN), which offers expanded clinical competence that can help improve the quality of health and care services. The book offers a range of perspectives on APN, APN models, APN education, challenges in the implementation of APN in new countries, as well as a description of the APN role, including areas of expertise. These core areas of the Caring APN model (clinical nursing practice; ethical decision-making; coaching and teaching; consultation; collaboration; case management; leadership; research and development) are described, together with the role of APN in acute care and primary healthcare service contexts. The book also explores the connection between epistemology, a three-dimensional view of knowledge (epistêmê, technê and phronesis) and a care perspective, as well as central theoretical aspects of nursing, e.g. health, holism and ethics/ethos.