This book, written by very well-known opinion leaders in the field, covers all aspects of periodic and non  periodic fevers, and related disorders. The expression refers to several different auto-inflammatory diseases, showing similar symptoms the primary symptom being a recurrent fever for an infectious cause cannot be found.  The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathogenesis derived from recent experimental studies and guides the reader through classification and nomenclature. A large part of the book is then devoted to a detailed description of the specific related diseases and their clinical presentations, the disease course, and potential complications in both pediatric and adult patients. The advice regarding treatment is based on the best currently available evidence in this constantly evolving area.