Wireless capsule cndoscopy closes the endoscopic gap between push enteroscopy and ileal intubation at colonoscopy and enables physicians to directly view the entire small intestine. This second issue of the Gastrointestinal Clinics of North America devoted to this topic includes the newest innovations in just the two years since the first issue published. Specific focus is on PillCam endoscopy and double balloon enteropathy. The Guest Editor, Dr. Jamie Barkin, has selected expert authors who have a wealth of experience with this major innovation in gastrointestinal endoscopy. Couple this with the first edition, published in 2004, and there are no other publications that more thoroughly discuss this technology!