This book highlights and suggests remedies for the racial and ethnic health disparities confronting people of color amid COVID-19 in the United States. Racial and ethnic health disparities stem from social conditions, not from racial features, that are deeply grounded in systemic racism, operating through the White racial frame. Race and ethnicity are significant factors in any review of health inequity and health inequality. Hence, any realistic end to racial health disparities lies beyond the scope of the health system and health care. The book explores structuration theory, which examines the duality between agency and structure as a possibly potent pathway toward dismantling systemic racism, the White racial frame, and racialized social systems.In particular, the author examines COVID-19 with a focus on the segregated health system of the US.