It is presently unthinkable to not take into account the need (sometimes mandatory) to implement Quality Management in Laboratories, either routinely or for research (basic and applied). Given that many countries have their own requirements regarding their mandatory implementation of Laboratory Quality Management Systems, this reality currently has a global reach to ensure the reliability of analytical results, especially since the effects of an analytical result can have major impacts on the environmental, pharmaceutical, forensic, clinical analysis, food areas, and so forth. In light of the latest findings for Laboratory Quality Management, in this English edition of the book I intend to present this data in an informative manner, within the operating framework of a Management System, and in line with the proposal of being a book that provides assistance to the new professionals in this area (highlighting, for example, the evolution of concepts, needs and basic structure of a Quality Management System), as well as assist experts seeking new tools for Laboratory Quality Management (highlighting, for example, the Analytical Quality Assurance Cycle and Quality indicators concepts, in addition to the numerous tools applied to auditing, training, corrective action and others).