ESCAPE-20 is the most recent in a series of conferences that serves as a forum for engineers, scientists, researchers, managers and students from academia and industry to present and discuss progress being made in the area of ";Computer Aided Process Engineering"; (CAPE). CAPE covers computer-aided methods, algorithms and techniques related to process and product engineering. The ESCAPE-20 scientific program reflects the strategic objectives of the CAPE Working Party: to check the status of historically consolidated topics by means of their industrial application and to evaluate their emerging issues.