The second edition contains a new chapter on pediatrics, a new chapter on commonly asked questions, revision to reflect the updated guidelines of the American Society of Anesthesiology, descriptions and photos of the most recent equipment, and updated information on issues of biohazards. The chapter titles include manufacturing and distribution of N2O and O2 gases, patient assessment, N2O abuse issues, titration of N2O/O2 gases, recovery from sedation, and multidisciplinary application. The volume is well illustrated with b&w photos. Clark teaches at the U. of Colorado Health Sciences Center, Brunick teaches at the U. of South Dakota.