Pediatric Chest Pain is reviewed in this issue of Pediatric Clinics, guest edited by Drs. Guy Eslick and Steven Selbst. Authorities in the field have come together to pen articles addressing the Epidemiology and risk factors for pediatric chest pain, Approaches to the pediatric patient with chest pain, Psychological causes of pediatric chest pain, Myocardial Ischemia (including Kawasaki’s Disease), Myocarditis and Pericarditis, Arrhythmias, Gastroesophageal Reflux and Foreign Body, Asthma and pneumonia, Pneumothorax/Pneumomediastinum/pulmonary embolism, Musculoskeletal causes of pediatric chest pain, Miscellaneous causes of chest pain, and Future Developments.