The second edition of The Practice of Medicinal Chemistry, edited by Professor Camille G Wermuth, provides a unique and comprehensive discussion of the practical problems facing today's medicinal chemists, from the conception of new molecules through to the production of new drugs and their legal/economic implications. The new edition of The Practice of Medicinal Chemistry has been updated, expanded and refocused to reflect developments over the nine years since the first edition was published. Experts in the field give personal accounts of both traditional methodologies and the newest discovery and development technologies providing us with an insight into medicinal chemistry, usually only gained from years of practical experience. This book is essential for organic chemists beginning a career in drug research and for medicinal chemists.