Pharmacology, 4th Edition helps you master the "must-know" concepts in this subject and how they apply to everyday clinical problem solving and decision making. This concise yet comprehensive text clearly explains and illustrates challenging concepts and helps you retain the material - from course exams and the USMLE Step 1 right through to clinical practice. New To This Edition: Learn the latest pharmacologic mechanisms and applications with new and updated drug information throughout. Be aware of new "off label" uses, including important FDA regulations.