The second edition of this atlas has been extensively revised to provide an up-to-date and comprehensive overview of therapeutic gastrointestinal endoscopy for upper and lower gastrointestinal diseases. The coverage ranges from basic but highly effective procedures like cold snare polypectomy and variceal ligation to sophisticated procedures such as peroral endoscopic myotomy and endoscopic submucosal dissection. New instruments, for example over-the-scope clips and various stents, are introduced in the relevant chapters. Furthermore, several chapters have been added to cover cutting-edge technologies for endoscopic treatment of complex conditions, including refractory gastroesophageal reflux disease and duodenal neoplasia. Many pictures have been exchanged for newer ones, most of them high-definition endoscopy photos, and schematic illustrations are used to ensure clear understanding of complex therapeutic procedures.