"The editor's purpose is to provide the reader with the latest information about SLE, its science, presentation, and treatment.This edition of Systemic Lupus Erythematosus continues to be an up-to-date, comprehensive, and well-referenced resource for both the basic science and clinical medicine aspects of this complex disease. The book takes us on a journey starting with the disease pathogenesis, continuing with animal models of lupus, various autoantibodies and antigens, the clinical approach to diagnosis and the affected organs and tissues, and ending with current therapies. It will be an excellent reference book for students of immunology/rheumatology and for experienced research scientists and clinicians. Reflecting the emerging information in this dynamic field, the volume includes new chapters on fibromyalgia and osteoporosis in association with SLE, and enhanced chapters on the molecular aspects of the cellular immunology of SLE, the neuropsychiatric aspects of SLE, and the various aspects of antiphospholipid syndrome. The addition of a searchable CD-ROM makes it easier to identify the updated information and to download the images for educational purposes. The chapters are written by experts in their respective fields, and each chapter independently represents a piece of the lupus puzzle. As Dr Lahita states in the introduction, "Reading the chapters in this book will not solve the mystery, but it will give you the impression that we are close to understanding the illness."