The purpose of this book is to provide public health, disability, and rehabilitation professionals and practitioners evidence-based science with respect to health disparities faced by people with disabilities, especially people with mobility limitations; alternative methods of rehabilitation and exercise science for this population; assistive device technology; and, improved access to health care, employment, and social participation.<div> </div>According to the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR), approximately 57 million Americans live with a disability. Disability severity and types vary considerably, such that each individual with a disability faces unique physical, social, and environmental barriers in order to enjoy quality of life and full participation in society. A large research literature shows that people with disabilities face substantial employment and health disparities compared to people without disabilities.