The focus of this issue is on some of the most challenging and controversial surgical procedures that surgeons face and for which there are multiple, unique approaches----webs and contractures, closed reduction of hand fractures, reflex sympathetic dystrophy, and upper limb injury and reconstruction. The editor has chosen to make this volume particularly future-facing through the inclusion of such topics as hand transplantation, outcomes, decision making, research possibilities, and randomized clinical trials. Essential reading for hand surgeons in addition to plastic surgeons.